We are pleased to announce that the 8th Annual Conference will be held again this year. (Venue and online)
Anyone is welcome to attend, not only healthcare professionals, but also the general public, students, etc.
◼︎Date and time
Sunday, September 22, 2024
Start 11:00 am (Registration 10:00 am) – Closing at 17:00 pm
*General Meeting: Held before the Annual Conference (members only)
※Reception: 5:30 p.m. start
Everyone is welcome to attend. (Limited to the first 100 people)
◼︎venue
Rihga Royal Hotel Osaka
5-3-68 Nakanoshima, Kita-ku, Osaka 530-0005, Japan
Access here
Free shuttle bus from JR Osaka here
Parking information
◼︎Greetings from the Representative Director
We are pleased to announce that the Intestinal Flora Transplantation Clinical Research Society of Japan is celebrating its 8th Annual Conference. We would like to express our gratitude for the support and cooperation of patients who have undergone transplantation, physicians and other medical professionals affiliated with the study group, supporting members, and the general public.
Our research group was the first private organization in Japan to systematically engage in intestinal microflora transplantation. In May last year, doctors belonging to our research group started a clinical study of “a novel fecal microbiota transplantation method using nanobubble water (NanoGAS® water)” (novel FMT method) for children with autism spectrum disorder aged 5 to 12 years, without using antimicrobial agents commonly used in conventional methods. Unlike conventional methods, this new FMT method does not require administration of antimicrobial agents or intestinal cleansing as a pretreatment, and is a new technology that is effective with a small dose, about 1/1000 of the conventional dosage.
This year, we have successfully completed this specific clinical study, and we are pleased to report the results to you. As a result of our research, the novel FMT method has shown promising results in autism spectrum disorder. We also plan to publish these results in an international paper to share them with the world. Furthermore, we will continue our clinical validation of intestinal microbiota transplantation for cancer and various other diseases in the future.
We would like to ask for your continued support and cooperation.
◼︎Schedule
| 10:30 Doors open |
| 11:00- ＜Morning Session＞ |
| Opening Remarks Representative Director: Zen Tanaka (President, Tanaka Clinic, Jinseikai Medical Corporation) |
| Possibility of intestinal microflora transplantation in cancer treatment Noriaki Yorozu (Director, Yorozu Clinic, Medical Corporation Iryushinkai) |
| A case report of breast cancer in which transplantation of intestinal microbiota was effective Zen Tanaka (President, Tanaka Clinic, Jinseikai Medical Corporation) |
| Supporting health by “drinking” gas Reduction of oxidative stress by “Hydrogen NanoGAS®︎ water” and its general use Risako Morishita (Researcher, Symbiosis, Inc.) |
| To the Bacteria Called “Bad Bacteria 〜Are you a “culprit”? Mysteries of the intestinal ecosystem Chihiro Yamamoto (Senior Researcher, Symbiosis, Inc.) |
| Intestinal flora test and early detection of cancer Makoto Shimizu (Senior Researcher, Symbiosis, Inc.) |
| Lunch break (boxed lunch included) |
| Company introductions |
| Lunchtime Talk Session The Magic Time of Le Cooker: Make, Eat, and Smile Naomi Hatanaka (Representative of Challenged LIFE) Chisato Suginohara (Representative of Miichan’s Sweets Studio) Sachiko Taki (Representative of General Incorporated Association Kodomo ni Naru) |
| ＜Afternoon Session＞ |
| Keynote Speech Developmental Disabilities: Seeing, Looking, Watching, Diagnosing, and Dr. Satoru Hirayama Osaka Maternal and Child Health Center Osaka Maternal and Child Medical Center Deputy Director, Department of Children’s Mental Health Clinical Study Report on the Efficacy and Safety of a Novel Fecal Microbiota Transplantation Method for Autism |
| Spectrum Disorders Efficacy and Safety of a Novel Fecal Microbiota Transplantation Method for Autism Spectrum Disorders Masahiko Shirotani (Director, Luke’s Ashiya Clinic) |
| Panel Discussion and Q&A |
| Future initiatives (from members) |
| Closing remarks Masahiko Johya, Executive Director (Director, Luke’s Ashiya Clinic) |
*The content and order of presentations are subject to change.
◼︎Speakers
Possibility of intestinal microflora transplantation
The Potential of Intestinal Microbiota Transplantation in Cancer Therapy
Noriaki Yorozu
Medical Corporation Iryushinkai Yorozu Clinic director
The importance of immunity in the treatment of cancer has been the focus of much attention. However, there is a wide range of applicable therapies depending on the stage of cancer: prevention, early stage, advanced stage, and terminal stage. Among them, gut microbiota transplantation (FMT) is expected to be a new treatment option. In this presentation, we will give our views on how gut microbiota transplantation in particular can contribute to cancer treatment, along with (immuno-)therapeutic options at each stage of cancer, with the latest research results. The impact of gut microbiota regulation on immunity and its clinical significance will be discussed.Breast Cancer Case Report
Case report of breast cancer in which transplantation of intestinal microbiota was effective.
Yoshinori Tanaka
Medical Corporation Nizenkai Tanaka Clinic board chairman
The addition of intestinal microflora transplantation to cancer treatment has the potential to prevent the onset of cancer, enhance the effectiveness of other cancer treatment methods, prevent cancer recurrence and metastasis, and improve QOL (quality of life). We aim to improve immune and metabolic functions through intestinal microflora transplantation and make it one of the useful treatments for cancer patients. In this presentation, we will present a case study of the use of intestinal microbiota transplantation in a patient with breast cancer.Hydrogen NanoGAS® Basic Research
Drinking
Risako Morishita
Symbiosis, Inc. researcher
Nanobubbles,” which are minute bubbles less than 1 μm in size and known for their long-term stability in water, can be filled with any gas. Synbiosis, Inc. has developed NanoGAS®︎ nanobubbles that are more stable over the long term using a patented manufacturing method, and has evolved a gas that is generally difficult to ingest into a “drinkable” form by enclosing hydrogen, which has antioxidant properties, in the bubbles. In the NanoGAS®︎ Basic Research, we will report the results obtained to date regarding the oxidative stress reduction effects of drinking hydrogen NanoGAS®︎ water, as well as the potential for general use.To the bacteria called “bad bacteria
Chihiro Yamamoto
Symbiosis, Inc. Principal Investigator
Is Baikinman evil?Animations and movies often have villains. They certainly do harm to the protagonist’s side, and sometimes they even enjoy it. But reality is a bit more complicated. When we find the “bad side” of things, we tend to confuse its existence with that of evil. What are these bacteria called “bad bacteria” doing to us? Are they evil at all times? Why are they there? As a stepping stone to deciphering the complex intestinal ecosystem, I would like to briefly introduce the bacteria called bad bacteria.
Intestinal flora testing and early detection of cancer
Intestinal flora testing and early detection of cancer
Makoto Shimizu
Symbiosis, Inc. Principal Investigator
With the popularization of “intestinal activity,” topics related to bacteria are now heard on a daily basis. When I recall the days of preparing culture media for bacteriological tests in dark laboratories and taking care of interns, I realize that the image of bacteria and microorganisms has changed dramatically. Technical terms such as “quorum sensing” and “chemical signaling processes” have become commonplace, and the capabilities and roles of bacteria are being reevaluated. We believe that intestinal bacteria are essential to human health, and that appreciating their symbiosis and creating a living environment for them is the key to maintaining good health. Binge eating is a source of fasting and fasting water. We will discuss the possibilities of a flora balance test.Lunchtime Talk Session
“Make, Eat, and Smile: The Magical Hours of Le Cooker.”
In this talk session, three women who are working for the joy of cooking, eating, and spreading smiles and children will share their thoughts and experiences.
Profile of Speakers
Naomi Hatanaka
General Incorporated Association Challenged LIFE representative
In the midst of raising three siblings, ages 12 (autistic/intellectual), 7, and 4. As a career consultant and diversity communicator, she has been a training instructor and consultant for companies and government offices throughout Japan. She also founded Challenged LIFE in response to her own child’s disability, and works under the philosophy of “From the perspective of people with developmental disabilities, we can make life easier for everyone. He also founded Challenged LIFE, a company that works with companies and schools to connect them with companies and schools. She has been involved in the launch of various projects that connect companies and businesses, and companies and schools, and is also involved in a wide range of other activities, such as being interviewed for the Nippon Television drama “Arisu in the Kitchen,” which will be broadcast from January to March 2024.Profile of Speakers
Chisato Suginohara
Miichan’s Confectionery Workshop representative
Resident of Shiga Prefecture, mother of 3 children in a family of 5 (Miichan’s mother), active company employee. Pre-opened “Miichan’s Confectionery Workshop” in January 2020 while working full time. In addition to her main job, she supports Mii-chan, who is unable to communicate with anyone but her family as the owner of a cake shop. In March 2023, Mii-chan graduated from compulsory education and held a grand opening.He also makes use of his experience to conduct social contribution activities for young people. In June 2024, she opened “Miichan’s Confectionery Workshop” and started the Sweets Kids’ Lab experience program as a place for children to learn.
Author of “Miichan’s Confectionery Workshop” The Birth of a 12-Year-Old Pastry Chef: Unlearning to Raise a Child
Profile of Speakers
Sachiko Taki
General Incorporated Association Become a Childrepresentative
Child Development Support and After-School Daycare Service Le Cooker person in charge (of an area of responsibility, but not necessarily supervising other staff)
Born in Yonago City, Tottori Prefecture in 1981, she is a mother of three children, a high school senior, a high school freshman, and a fourth grader.While working with families with living difficulties and people with disabilities, she saw that the ordinary was not the norm, and keenly realized that “childcare is about people”. She became a freelance childcare worker. She continues to practice “not to leave anyone alone” as a member of both the government and private sectors. She also provides her practice to companies, etc., so that Le Clos’s new form of welfare can become a model case. Provides support and consultation to families in need. Conducting social studies field trips that connect children and businesses. Supporting children with disabilities and their parents in our restaurant-based welfare business. We value our philosophy, “Never leave anyone alone”, and we are committed to being close to those who are most anxious.
keynote speech
Mr. Tetsu Hirayama
Osaka Prefectural Hospital Organizationrepresentative
Osaka Maternal and Child Health Center, Department of Children’s Mental HealthDeputy Minister
Based on his many years of experience as a clinician, he will speak from the perspective of “the major implications of seeing the child,” which include “seeing the child directly, seeing what the child is expressing, observing the child closely, diagnosing the child, and what to communicate to the child and parents afterwards.Report on Specific Clinical Research Results
Report on the results of a specific clinical study on the efficacy and safety of a novel fecal microbiota transplantation method for autism spectrum disorder.
Masahiko Shirotani
Luke’s Ashiya Clinic director
In the “Specific Clinical Study on the Efficacy and Safety of a Novel Fecal Microbiota Transplantation Method (FMT) for Autism Spectrum Disorders (ASD),” which began in May 2023, a fecal microbiota solution (SHIN-1) containing hydrogen nanobubble water was used and applied to 30 ASD children in the severe, moderate and normal range, resulting in a statistically significantly reduced by approximately 30%. In particular, 19 of 28 children in the severe range (approximately 68%) had a mild disease, making this a safe and less invasive treatment method that is attracting attention. This novel FMT method is expected to be applied not only to ASD treatment but also to other diseases.Future Initiatives
Possibility of intestinal microflora transplantation
Masayuki Asaue Holm（LAGOM Life Clinic Tateshina, Chairman of the Board of Directors）
Yuichi Kawai（Medical Corporation Yuakai Cute Internal Medicine Clinic, Chairman of the Board of Directors）
Yoshitaka Fukuzawa（Director and Professor Emeritus, Aichi Medical University）「Future Challenges and Prospects in the Usefulness of FMT」
Get-together
Get-together
Everyone is welcome to attend the reception after the scientific meeting. At the reception, a hydrogen NanoGAS water tasting corner will be set up by Symbiosis, Inc. Hydrogen NanoGAS water is the fundamental technology that supports the FMT of this research group. We are also working on the verification of its application to various industries other than medical care. Last year, we were selected for a NEDO (National Institute for Research Advancement) funded project to verify the possibility of using hydrogen NanoGAS water to maintain the flavor of Japanese sake and wine after opening the bottle. Visitors can experience a taste comparison corner where the flavor of alcohols, coffee, and other beverages can be changed by adding a small amount of hydrogen NanoGAS water. Please come and experience the potential of hydrogen NanoGAS water that supports our FMT method. If you wish to attend the reception, you need to register and pay for the reception separately from the registration for the Annual Conference.
*Speakers’ speeches will be posted as soon as they are confirmed.
◼︎Registration and Participation Fee
◼︎Sponsor Booths
Happi and Project Inc.
MAMORU “Yugon White Paper®” on the Future of People with Disabilities without ParentsThe biggest concern for parents of children with disabilities is, “What will happen to this child when we are gone?” . The Oyanaki “Yugon White Paper®” is a sheet that allows people with disabilities to leave behind information in a “simple, easy, and reliable” checklist format so that those around them can understand and support them.
https://yuigonhakusho.com/oyanaki.html
Symbiosis, Inc.
Hydrogen NanoGAS waterHydrogen NanoGAS water is the basis of fecal microflora transplantation and is being applied beyond medicine; NEDO grant verified flavor maintenance of sake and wine, and found that the addition of the water changes the flavor. Consultations are available by appointment on the day of the conference.
Reservation form in preparation
Miichan's Confectionery Workshop
A small cake shop in Shiga Prefecture with a floor space of 5 tsubo. Mii-chan, the patissier and manager, is shy. Although she cannot talk to customers, she communicates with them through cakes. On the day of the event, we will be serving baked goods. We will be selling our very popular financiers, Kobo sablé, etc!Our entire staff will be waiting for you.
https://mi-okashi.com/
French Restaurant Le Clos Group
Owner-chef Isao Kuroiwa opened the welfare office out of his desire to create an environment where people with and without disabilities can work together. At the welfare office in Tenmabashi, users called “cast members” are involved in a wide range of work, including food preparation, dessert making, and customer service. On the day of the event, we will prepare baked sweets (5 kinds of handmade cookies that are very popular)!https://fooding.co.jp/
The Japanese Society of Preemptive Clinical Medicine, Inc.
Based on the principle of helping cancer refugees and patients with intractable diseases for which no effective standard treatment is currently available, we aim to contribute to the academic development of Japan and the health of the nation by developing effective preventive methods, testing methods, and treatments and conducting clinical research from the perspective of preventive medicine, which is to predict, diagnose, preempt, and intervene before the onset of diseases that are likely to occur in the future. The Society’s activities are aimed at contributing to the academic development of Japan and the improvement of the health of the nation’s people through the development and clinical research of effective preventive methods, testing methods, and treatments from the perspective of preventive medicine, which is to predict, diagnose, and intervene in advance. We hold an academic conference every year to provide a forum for discussion of the latest information both domestically and internationally.https://jspcm.org/
Genmai Enzyme Co.
Genzyme High GenkiGenmai Enzyme Co., Ltd. was founded in 1971. Genmai Enzyme, a dietary supplement made from brown rice, germ, and epidermis fermented with yeast, is an easily digestible health supplement and is produced at the company’s factory in Hokkaido, Japan. No pesticides have been detected in the product and no food additives are used. Please feel free to consume it.
https://www.genmaikoso.co.jp/
Otaka Enzyme Co.
Tradition and Trust Brand “Odaka EnzymeBorn in Hokkaido, Japan, Odaka Enzyme is a pioneer company that created the first plant fermented extract in Japan.
We hope to contribute to health and beauty through plant fermented beverages produced by a process that has remained unchanged for about 100 years.
We will be offering tastings on the day of the event.
https://www.ohtakakohso.co.jp/
Life Wellness Six Lives of Health
Rokumei Kenko Hoho®, the world’s highest level of natural medicine with a royal warrant from the British Royal Family, 6 ways of life and 2 types of health for each type of constitution. Why don’t you develop lifelong health habits that suit you, improve your unwellness, prevent illness, avoid being bedridden, and extend your healthy life span? Lifestyle is the key to health! Rokumei Kenko Hoho® aims to make healthy living a part of Japanese culture.https://jlwa.jp/
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