Renal Disease Initiatives


Active treatment to inhibit the progression of renal function for conservative chronic renal failure is currently mainly treatment for hypertension, hyperkalemia, renal anemia, hypocalcemia, and hyperphosphatemia in the current insurance system.
This time, by changing the diversity and balance of gut flora with FMT, we expect to suppress nephritis by immunity, excrete uremic substances, adjust acid-base equilibrium, adjust electrolyte balance, improve renal anemia, suppress renal function decline, and thereby avoid or delay the introduction of dialysis therapy due to end-stage renal failure as much as possible. Or we hope to delay the introduction of dialysis therapy due to end-stage renal failure as much as possible.

Target group

Renal function is serum creatinine 2~8mg/dl
(eGFR<30, strictly speaking, eGFR measurement from cystatin C is preferable)
Male and female patients are acceptable.
Age: 20~60 years old
Primary disease: chronic glomerulonephritis (diabetic nephropathy if desired)


Prior to FMT, a gut flora balance test is performed, the donor is determined accordingly, and a bacterial solution is prepared.
Patients are asked to fill out a quality of life questionnaire.
FMT is performed once a week (6 times), and after the 7th FMT, after consultation with the attending physician, FMT is continued once every 2 weeks for 3 times.
(for a total of 3 months)
Renal function is evaluated according to the above.


Transplantation fee: 6 times course 1,562,000 yen, additional 110,000 yen/time after the 7th transplant
Flora balance examination fee: 55,000 yen
Other medical examinations and tests not included in the transplantation fee

Read more

If you are willing to cooperate with our 2-year check inspection

Two gut flora balance tests after transplantation will be provided free of charge.
One more box of hydrogen NanoGAS® water will be provided free of charge in addition to the one box included in the transplant cost.

*The cost of the transplant procedure will be billed to you by the Association for Clinical Research of Fecal Microbiota Transplantation Japan.
Please be sure to check our cancellation policy before applying.

*Consultation fees by a medical specialist (transplant consultation, nutritional guidance, etc.) will be charged separately.
*Gut flora transplantation (fecal microbiota transplantation) is a method undergoing clinical trials at university hospitals and other facilities nationwide, and transplantation at our study group is positioned as free medical care.

Visit this page for more information on the clinic’s transplantation process and costs.

These are medical institutions where intestinal flora transplants are available.
All medical institutions use a bacterial solution manufactured by the exclusive research institute of the Intestinal Flora Transplantation Clinical Research Association following a standardized procedure.
In addition to the transplantation fee, any consultation with specialists (transplantation consultation, nutritional guidance, etc.) will be charged separately.

Kanto region (including Tokyo, Kanagawa, Saitama, Gunma, Tochigi and Chiba prefectures)

Tokyo metropolitan area

Futamatakai Medical Corporation Natural Art Clinic

(integrative medicine, nutritional therapy, internal medicine, pain clinic)

Postal Code 102-0085
Android Building 2F, 6-5 Rokubancho, Chiyoda-ku, Tokyo


  • Consultation fee: 5,500 yen (including tax)/15 minutes *First-time patients will be charged a separate registration fee of 3,300 yen (including tax) for the first visit.
  • Nutritional guidance: yes, Psychological counseling: yes
  • Features: nutritional therapy (orthomolecular, supplement therapy), functional medicine, IV therapy, dietary guidance, natural hormone therapy, hydrogen therapy, natural herbal therapy, chelation therapy (detoxification), Ayurveda, far-reaching therapies, Yamamoto New Scalp Acupuncture (YNSA), plasma therapy
Click here to visit the Natural Art Clinic website.

Chubu region(including Aichi, Nagano, Shizuoka, Niigata, Toyama, Ishikawa and Fukui prefectures)

Nagano prefecture (Chuubu area)

Medical Corporation Lagom Life Clinic Tateshina

(Internal medicine, gastroenterology, pediatrics)

Postal Code 391-0213
3317-1 Toyohira, Chino-shi, Nagano, Japan


  • Consultation fee: The initial consultation fee is 5,100 yen (all prices below include tax) for a maximum of 30 minutes. An additional consultation fee of 3,100 yen per 15 minutes will be charged for an extension of consultation time.
Click here to visit the Life Clinic Tateshina website.
Fukui prefecture (Hokuriku area)

Medical Corporation Shishokai Kimura Hospital

(Gastroenterology, surgery, anti-aging)

Postal Code 919-0634
57-25 Kitakanetsu, Awara City, Fukui Prefecture


  • Consultation fee: 5,500 yen for the first visit, 3,300 yen for the second visit (tax included)
  • Nutritional guidance: Yes
  • Features: Endoscopy available
For the Kimura Hospital website, click here.
Aichi prefecture (Chuubu area)

Medical Corporation Keimeikai Kimura Hospital

(Gastroenterology, orthopedics, dermatology)

Nagoya, Aichi 465-0087, Japan
2-22-1, Meitohondori, Meito-ku, Nagoya-shi, Aichi, Japan


  • Consultation fee: 5,500 yen (tax included)/30 min.
  • Nutritional guidance: Yes
  • Features: Primary care (from prevention to rehabilitation) in the community
Click here for the website of Medical Corporation Keimeikai Kimura Hospital

Takagi Surgical and Internal Medicine Clinic

(Neurosurgery, surgery, internal medicine)

Okazaki, Aichi 444-0008, Japan
27-2, Aza Higashimaeida, Doro-cho, Okazaki-shi, Aichi, Japan


  • Consultation fee: Please contact Takagi Surgical Clinic directly.
Click here for the Takagi Surgical and Medical Clinic website

Kansai region (south-western half of Japan, including Osaka)

Osaka metropolitan area

Medical Corporation Nizenkai Tanaka Clinic

(Internal medicine, cardiology, allergies, physiatry)

2-3-8, Ikuno-nishi, Ikuno-ku, Ikuno-ku, Osaka-shi,
Osaka 544-0024


  • Consultation fee: 8,800 yen (tax included)
  • Nutritional guidance: Yes
  • Features: nutritional therapy, supplement prescription, intravenous therapy, immunotherapy
Click here to visit the Tanaka Clinic website.

Medical Corporation Yuakai Cute Internal Medicine Clinic

(Internal medicine and gastroenterology)

Postal Code 536-0023
3-7-14 Higashinakahama, Joto-ku, Osaka-shi, Osaka


  • Consultation fee: 8,800 yen (tax included)
  • Online: Yes
  • Nutritional guidance: Yes
  • Features: Gastrointestinal and colonoscopy available
Click here to visit the website of the Kawauchi Internal Medicine Clinic.

Dr. Reiko Haruna, Deputy Director of theHaruna Clinic!

(Pediatrics, allergies, internal medicine)

Osaka, Japan 532-0006
Room 202, Core Wing Aoyama, 1-3-13 Nishimikuni, Yodogawa-ku, Osaka-shi, Osaka


  • Consultation fee: 5,500 yen (tax included)/20 minutes *Additional fee for every 10 minutes ( Refer to the website )
  • Online: Yes
  • Nutritional guidance: Yes
  • Characteristics: Female doctor. We see both children and adults with allergic diseases such as atopic dermatitis, developmental disorders, adrenal fatigue, and other conditions that are not easily improved by western medicine. We also provide biomedical treatment and biomedical testing using Chinese herbal medicine, diet and lifestyle guidance, acupuncture, supplements, etc.
Click here to visit the Haruna Clinic website.

Tsubota Clinic

(Cardiology, dermatology, pediatrics)

Postal Code 547-0032
3-2-4 Nagare-cho, Hirano-ku, Osaka-shi, Osaka


  • Consultation fee: 5,500 yen (tax included)/30 min.
  • Nutritional guidance: Yes
  • Features: female doctor. She can perform cardiovascular examinations. She can perform toxic metal testing (Blood Metal Panel Test and Tri mercury test).
Click here to visit the Tsubota Clinic website.
Hyogo prefecture (Kinki area) (Hyougo)

Luke's Ashiya Clinic

(Internal medicine, gastroenterology, psychosomatic medicine)

Postal Code 659-0092
2F Moo Building, 8-2 Oharacho, Ashiya-shi, Hyogo, Japan


  • Consultation fee: 22,000 yen (tax included) / 1 hour * AGEs measurement and InBody measurement are performed.
  • Online: Yes
  • Nutritional guidance: yes, Psychological counseling: yes
  • Characteristics: in addition to nutritional therapy based on molecular nutrition, IV therapy, hydrogen therapy (intravenous drip), reduced electron therapy, psychotherapy (cognitive behavioral therapy, Simonton therapy, box garden therapy, EMDR, etc.), etc.
Click here to visit the Luke's Ashiya Clinic website.

Chugoku region

Tottori prefecture (Chuugoku area)

Medical Corporation Iryushinkai Yorozu Clinic

(Internal medicine, gastroenterology, cancer integrative oncology gastroenterology)

Postal Code 689-0202
1-118-4, Mihagino, Tottori City, Tottori Prefecture


  • Consultation fee: 4,950 yen (tax included)
  • Nutritional guidance: yes, Psychological counseling: yes
  • Characteristics: Can be implanted after endoscopy or intestinal cleansing with a special machine.
Click here to visit the Yorozu Clinic website.

Kyushu/Okinawa Region

Fukuoka prefecture (Kyushu)

Medical Corporation Kiwakai Kitamura Clinic

(Gastroenterology, surgery, oncology)

4-3-8 Nishiki-cho, Onojo-shi, Fukuoka 816-0935 , Japan


  • Consultation fee: Please contact Kitamura Clinic directly.
Click here to visit the Kitamura Clinic website.
Kumamoto prefecture (Kyushu)

Grace Medical Clinic

(Internal medicine, pediatrics, cardiology)

Postal Code 862-0916
1-16-36 Sadohara, Higashi-ku, Kumamoto-shi, Kumamoto


  • Consultation fee: 5,500 yen (tax included)/30 min.
  • Online: Yes
  • Nutritional guidance: Yes
  • Features: nutritional therapy, supplement prescription, intravenous therapy, immunotherapy, gastrointestinal and colonoscopy, etc.
Click here to visit the Grace Medical Clinic website.

These are consultation facilities where you can ask questions about transplants, determine whether transplants are right for you, and discuss other issues from the perspective of your field of expertise.
Please note that we may not be able to respond to inquiries outside of our field of expertise.

Information and Access to Materials Related to this Research
During the course of your participation in this initiative, if we learn of any new information that may affect your willingness to continue your participation, we will notify you immediately. If we receive important information regarding this initiative, we will re-evaluate your willingness to continue your participation.
If you would like more detailed information about this initiative, please contact your physician or other health care provider.
We will only disclose such information to the extent that the personal information of other subjects is protected and the originality of the study is maintained.

Regarding the viewing of records of this initiative and other information by third parties
In order to confirm that this initiative is being carried out properly while protecting the human rights of patients, related parties, government agencies, and others may view your medical records and other information. However, these parties are obliged to maintain confidentiality, so the patient’s name and other privacy-related information will be protected.

Handling of Personal Information
Your data obtained through this initiative may be published in medical journals, but your privacy will be protected because we will not reveal any personal information such as your name.
Regarding the information collected from the data and medical records you provide, all personally identifiable information (name, date of birth, address, etc.) will be excluded from these, and instead a registration number will be assigned exclusively to this study group, so that it is impossible to know who the stool sample and information belong to.
However, a correspondence table that can link the individual to the registration number will be created and retained so that the individual can be identified when necessary. (This is called “linkable anonymization.”)
In this way, due attention will be paid to the protection of personal information.

Storage and Disposal of Samples and Information
Materials and data obtained in this effort will be stored for at least 10 years from the final publication of the results of this research.
Careful consideration will be given to the protection of personal information when storing and disposing of data and other materials.

Requests during the transplant period
Please notify us if your oral medication changes during the study period.
Please inform your doctor if you have taken antibiotics or if a new intestinal regimen has been added or removed.

Before FMT, 3 months after, and 6 months after
Gut flora balance test
Blood test
Quality of life questionnaire (attached)
< Inspection items >
Urinalysis (general qualitative, urinary sedimentoscopy)
Blood test
General biochemical tests (TP, Alb, T-Cho, Na-Cl, K, Ca, BUN, UA, Cre, P, glucose, eGFR, cystatin C)

Drink 200 cc of hydrogen NanoGAS® water per day (during the transplant period)
Answer the questions in the Bacterial Power Up Diary online.
(answered one day before the transplantation date answered once every two weeks after the transplantation is completed)

To be completed daily by the patient for each transplant
(Bristol Scale must be filled out daily)
Filled out twice a week after completion of transplantation

【Method for Reply】
The response method form can be used on PCs, tablets, and smartphones, and is linked to kintone.

Please read the QR code below or enter the URL directly in your browser.


Related Sites

Website for Healthcare Professionals