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[Event] Crowdfunding Request for Cooperation

The project has been closed*. ▼ Updates ▼2022/6/24 Added event notice and report. WE HAVE DECIDED TO CHALLENGE CROWDFUNDING IN ORDER TO PROMOTE RESEARCH ACTIVITIES TO MAKE THIS TREATMENT AVAILABLE TO ALL CHILDREN DIAGNOSED WITH ASD AS QUICKLY AND SAFELY AS POSSIBLE. At present, the cost of transplantation is a significant burden due to the…

The project has been closed*.

▼ Updates ▼
2022/6/24 Added event notice and report.

WE HAVE DECIDED TO CHALLENGE CROWDFUNDING IN ORDER TO PROMOTE RESEARCH ACTIVITIES TO MAKE THIS TREATMENT AVAILABLE TO ALL CHILDREN DIAGNOSED WITH ASD AS QUICKLY AND SAFELY AS POSSIBLE.

At present, the cost of transplantation is a significant burden due to the free treatment, and it is not easy to receive intestinal flora transplantation.

The cost of transplantation is high due to fixed costs such as the cost of testing intestinal flora balance using next-generation sequencers, maintenance of donor specimens (JapanBiome), production costs of NanoGAS® water used in the bacterial solution for transplantation (plant maintenance costs, etc.), and personnel costs for managing the research group. The current situation is that the cost of transplantation has become expensive.

Not only in the clinical trials currently taking place at our affiliated medical institutions, but also through clinical research conducted at universities, with the goal of advancing to clinical trials and being recognized as medical care!!!

For those of you who have not had the opportunity to learn about intestinal flora transplantation, we are starting a crowdfunding campaign in the hopes that many people will receive a transplant, that this treatment will spread more widely, and that we can further our research!

We look forward to your warm support. Thank you in advance for your support.

Project Summary

Period] Saturday, May 14 – Sunday, July 10, 2022

Target Amount] 3,000,000 yen

[Purpose of use]
● Various testing costs ● Development costs of automatic purification equipment for bacterial solution ● Gazefinder trial session costs
● Maintenance costs for each plant ● Crowdfunding fees

<Project Implemenation and Period>
Your donation will be used to cover the cost of research to be conducted by the end of fiscal year 2022 (March 31, 2023), which is the end of this project.

Click here to support us (project page)

For return details and support, please click here to preview the page.
We appreciate your cooperation.

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Crowdfunding Support Message

From a Patient (Message of support)

I have seen children who have undergone intestinal flora transplantation grow up to be very successful. If I ever meet a child with autism spectrum disorder in the future, I will tell him or her that this is a very good treatment method for the child. I hope that this revolutionary intestinal flora transplantation will spread rapidly.

If intestinal flora transplants become available through insurance, many people will seek treatment. This is because there are so many possibilities for intestinal flora transplantation, including its application for cancer. However, I have heard that we need to collect more cases to bring transplantation to that stage. I know the road will be hard, but we need to increase the number of cases and bring the cost closer to the point where it is affordable. At the same time, research should be further developed. In this way, I hope that the number of people who want to undergo transplantation will increase, even if only by one person.

From Dr. Masahiko Johya, Director, Luke’s Ashiya Clinic (Video)

From Naomi Hatanaka, whose son experienced a transplant (Video)

event preview

July 5, 2022, “Second Annual Loose Fungi and Roundtable Discussion”

We are pleased to welcome Ms. Ai Kitamura, a fermented food specialist, to our online event with the theme of “A diet that makes your intestinal bacteria happy”.

Fermented foods that are good for you?
You mean yogurt or natto?
What are some easy cooking tips?

And so on… Whether you just want to listen or want to talk with us, you’re welcome…
Click the banner above for more information!

Event Report

June 15, 2022 “First Roundtable Discussion with Loose Fungi”

We held a “Roundtable Discussion with Loose Bacteria” online on Wednesday, June 15 at 12:00 p.m.
More than 40 people attended and sent us positive feedback that it was good to hear about the experiences of parents who have actually had transplants and that it has become an institution for learning about intestinal bacteria.

Some of the day’s videos are now available! Please click here to view.

May 14, 2022 Kick-off event

The kick-off event was held as follows.
We have received immediate support and would like to thank everyone for making this kick-off event a success.
We are planning to hold another event at the end of the crowdfunding period, so we hope you will join us.

▼ Kickoff Event

Date & Time] Saturday, May 14, 2022, 11:30 a.m. Opening

Participation fee] Free of charge

Place] Kobe Health Industry Development Center (Hidec) 2F Multipurpose Room (tentative)
6-7-4 Minatojima-Minami-cho, Chuo-ku, Kobe, Hyogo 650-0047, Japan
Kobe Health Industry Development Center (Hidec)

You can also participate online.

Contents】Trial use of the Gazefinder eye tracking device,
Mini seminar on ASD and intestinal bacteria, Roundtable discussion

HELD ONLINE AND AT THE VENUE, THE “UNDERSTANDING ASD AND INTESTINAL BACTERIA MINI-SEMINAR” FIELDED A VARIETY OF QUESTIONS.

Gazefinder is a device that objectively evaluates the characteristics of children with ASD by measuring eye movement. Since it only requires the child to watch a video projected on a monitor screen, even small children can be measured, and it is used in research on ASD and other disorders.

The study group uses Gazefinder to quantitatively evaluate changes before and after transplantation.

~Gazefinder measurement data before and after intestinal flora transplantation (FMT) ~
The viewpoints that could be measured appear as blue dots.
After transplantation (lower portion), the patient is able to see people’s eyes and mouth clearly.
ASD diagnostic criteria include difficulty with eye contact interactions and discrimination of gaze direction.
In the data below, before the transplant (top), the patient barely looked at the eyes, but after the transplant (bottom), there is a change in gaze direction, looking at the eyes and looking at the mouth.
This is a significant change for people with ASD, who often say that they feel discomfort and stress when making eye contact with others.

The Australian clinical trial for ASD evaluation using the Gazefinder eye tracking device has been completed, and an application for medical device approval has been filed with the Australian Medical Products Administration (TGA).

In addition, an application was filed with the Australian Medical Products Administration (TGA*4) for medical device approval for an ASD evaluation device based on the Gazefinder’s eye measurement technology.

1: University based in Melbourne, Victoria, Australia*2: Medical research institute based in Perth, Western Australia, Australia*3: Autism Spectrum Disorder*4: Australian Therapeutic Goods Administration Administration

Source: JVC KENWOOD Corporation https://www.jvckenwood.com/jp/press/2021/press-211011-01.html
https://www.jvckenwood.com/jp/press/2021/press-211011-01.html


Please click here to support us!

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    日々の診療の中で、従来の標準治療だけでは十分に対応しきれない慢性的な消化器疾患。特に、潰瘍性大腸炎や過敏性腸症候群(IBS)を患う人々は、検査数値や画像所見だけでは見えにくい深い不安と、生活上の大きな制限を抱え続けている。 城谷バイオウェルネスクリニックの城谷昌彦医師が「腸内フローラ移植(FMT)」という新たな治療領域に関心を持った大きなきっかけ―――それは、他でもない先生自身が回腸嚢炎の治療法の一つとしてFMTを自ら受けた経験にあった。 自ら患者としてFMTを体験した医師は、臨床でNanoGAS®-FMT(水素ナノバブル水を用いた腸内フローラ移植)をどう活かし、患者の人生をどう変えているのか。そして、なぜ今、期待ばかりをあおることなく「慎重なエビデンスの検証」を訴え続けるのか。 「医療の成果は、単に症状や検査数値の改善だけではありません。患者さんが本来取り組みたかったことに再び向き合えるようになること、将来に前向きな気持ちを持てるようになることこそが、非常に大切な成果なのです。」 城谷医師の医療哲学と、2026年9月に開催される「第10回 一般財団法人腸内フローラ移植臨床 学術大会」に向けた見どころに迫る。 数値や画像には映らない「患者の不安」に向き合う 自らがFMTを受けた経験―――腸内細菌という「切り札」 「私自身、回腸嚢炎に対する治療法の一つであるFMTを大学の治験を通じて受けたことが、腸内フローラ移植に関心を持つ大きなきっかけでした」と、自らの患者体験と、消化器専門医としての深い葛藤を振り返る。 日々の診療において、従来の標準治療だけではどうしても対応しきれない患者の症状や経過に向き合うことは決して少なくない。中でも、潰瘍性大腸炎やIBS(過敏性腸症候群)の患者は、内視鏡検査や血液検査の数値だけでは測れない「いつお腹が痛くなるか分からない」「外出や外食が怖い」といった日常生活上の制限や精神的な不安を常時抱えている。 「腸内フローラを整えることは、単なる消化器症状の改善にとどまらず、患者さんのQOL(生活の質)を根本から向上させる可能性を秘めている」。自らの体験と臨床での実感から、腸内細菌へのアプローチを従来の治療を補完する「切り札」の一つとして見出すようになった。 NanoGAS®-FMTという新たな選択肢の可能性 大学の治験でFMTを受けたものの、大きな改善は見られなかったが、その可能性を感じることはできたという。数あるFMTの中でNanoGAS®-FMTを導入した理由は、「臨床現場での扱いやすさ」と「患者への負担軽減」にあったという。 従来の移植法と比較しても、患者への心身の負担に配慮しながら実施できる可能性を感じたことが大きな決定打となった。これまで既存の治療法を試しても十分な改善が得られなかった患者に対して、「腸内環境の再構築」という全く新しい選択肢を提示できるようになった意義は極めて大きい。 しかし、城谷医師は戒めを忘れない。 「一方で、FMTを『万能の治療法』のように扱うべきではないとも考えています。すべての患者さんに同じ結果が出るわけではありませんし、適応の見極め、既存治療との組み合わせ、そして治療前後の評価は極めて慎重に行う必要があります」 将来への不安を抱えた若い潰瘍性大腸炎患者の劇的な変化…

If you are concerned about your intestinal flora, start by consulting us.

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