Prevention of rebound after dieting by transplantation of intestinal microflora by own stool



The question of whether a gut flora transplant can help you lose weight.

Endobacteria and obesity/slimness are very closely related.

In fact, the type and composition of the intestinal bacteria a person has determines the body’s ability to prevent weight gain and metabolize certain foods.

Jeffrey Gordon’s famous stool swap experiment between obese and thin mice. [1][1]

It is possible that losing weight, increasing metabolism, and becoming healthier are two separate issues.

Transplants using your own stools to lose weight.

In morbidly overweight cases, it has been reported that weight loss benefits can be seen by transplanting one’s own stool.

This effect prevents rebound.

Many people can work hard while dieting.
But then.
Most successful dieters rebound.
Furthermore, if the diet restricts the diet, the rebound can cause the body to revert back to its original state, making it more prone to weight gain.

Effects of Diet-Modulated Autologous Fecal Microbiota Transplantation on Weight Regain – Gastroenterology


The methodology for this experiment involved 90 overweight men and women assigned to three diets.

  1. Healthy Eating Diet
  2. Mediterranean diet
    …eat 28g of walnuts a day
  3. “Green” Mediterranean diet
    …Eat 28 grams of walnuts a day, drink green smoothies with Mizin Koukikusa.

All groups are given free gym memberships and exercise guidelines.

Their average age is 52 years old and they will be on this diet for 6 months.
They have lost an average of 8.3 kilos.

And this experiment includes a rebound period.
You would provide your own stool immediately after the first 6 months of dieting and then drink it from 6 to 14 months later.
There was no mention of the bacteria being killed by stomach acid due to oral administration.


Each of the three groups was provided with a placebo for observation, with the following results

Did autologous stool transplantation prevent rebound?

  • No significant difference in general diet improvement or Mediterranean diet
  • The “green” Mediterranean diet had a marked effect, with a 17.1% weight rebound on autologous stool transplants versus a 50% rebound on placebo
  • The same “green” Mediterranean diet also helps with waistline numbers and insulin rebound

Intestinal bacteria seem to be deeply involved in these results.

To see results from transplanting one’s own stool, one’s gut microbiome must have changed after six months on the diet.
It is this “green” Mediterranean diet that has significantly changed the subject’s own intestinal flora.

There is a clear change in metabolic improvement and anti-inflammatory effects.

This experiment was followed up with a later

The above experiment alone highlights only the benefits of the “green” Mediterranean diet, but in fact, all of the diets showed that autologous stool transplantation helped to maintain metabolism.

Autologous fecal microbiota transplantation can retain the metabolic achievements of dietary interventions – ScienceDirect

In this report, all three groups collectively have better metabolic maintenance values in autologous stool transplants than placebo.

  • Decrease in leptin (a substance secreted by fat cells)
  • Decrease in interleukin-6 (inflammation marker) values
  • Decrease in total cholesterol

In fact, various studies have already shown that in lifestyle-related diseases such as dyslipidemia and diabetes, inflammation occurs first in the body tissues.

Improved diet changes the intestinal flora.

The great thing about this experiment is that it showed that dietary changes can change the intestinal flora.

The number of people taking probiotics, taking prebiotics, and trying to improve their intestinal flora in the name of intestinal activity is increasing every year.

However, there is a growing realization that diet does not improve intestinal flora.

Diet alone cannot sustain changes in the intestinal flora.”

In this study, encapsulation of my own intestinal bacteria that had changed during the six months I had been improving my diet, and continued to be taken after the diet ended, showed metabolic maintenance and anti-inflammatory effects.

I think this can be said that the autologous fecal transplantation “reproduces the intestinal flora of the period of hard work”.

Overweight is not only due to a person’s weak will.
The composition of intestinal bacteria, antibiotics in foods, prescribed antibiotics, and various obesity factors have been noted.

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