- We are pioneers of stool transplants. [Just before the Annual Meeting, a glimpse Vol. 1
- Making Fecal Transplantation a Safe Treatment [Last-minute Glimpse before the Annual Meeting Vol. 2
- Atopy and Brain-Gut Correlation, Intestine-Dermal Correlation [Just before the Annual Meeting, Glimpse Vol. 3].
- Three cases of irritable bowel syndrome that showed improvement with transplantation [Flyer just before the Annual Meeting, Vol. 4].
Today, I would like to introduce Dr. Kitamura of the Kitamura Clinic in Fukuoka Prefecture.
Let me now introduce Dr. Kitamura’s abstract.
A case of autism treated with intestinal flora transplantation that improved symptoms.
Autism is a neurodevelopmental disorder, now called Autism Spectrum Disorders : ASD. The main symptoms include difficulties with social behavior and interpersonal communication, repetitive behaviors, and a strong preoccupation with certain things.
In recent years, the number of patients has been increasing not only in Japan but also worldwide, with a high incidence rate of 1 in 62 reported in Japan and 1 in 59 in the U.S., and the disease has been discussed as a social problem.
TREATMENT OPTIONS FOR ASD INCLUDE BEHAVIORAL, SPEECH, AND SOCIAL THERAPY, PSYCHIATRIC PHARMACOTHERAPY, AND DIETARY AND METABOLIC NUTRITIONAL THERAPY, BUT TREATMENT IS CHALLENGING.
The gut-brain relationship, in which the gut microbiota affects the brain in various ways, has become widely known, and abnormalities in the gut microbiota of ASD patients have been reported in many cases. Fecal microbiota transplantation (FMT) is a promising treatment to improve gastrointestinal and behavioral symptoms of ASD.
The University of Arizona followed ASD patients treated with Microbial Transfer Therapy (MTT) for two years and found improvement in gastrointestinal symptoms and a 45 percent improvement in social behavior. They also reported that ASD symptoms slowly improved after treatment.
IN THIS STUDY, A 7-YEAR-OLD FEMALE CHILD WITH ASD WAS TREATED WITH INTESTINAL FLORA TRANSPLANTATION. WE REPORT SOCIAL BEHAVIOR AND GASTROINTESTINAL SYMPTOMS THAT CHANGED OVER THE COURSE OF TREATMENT. THIS CASE SUGGESTS THAT INTESTINAL FLORA TRANSPLANTATION MAY BE EFFECTIVE IN THE TREATMENT OF ASD.