{"id":4611,"date":"2026-01-15T13:20:06","date_gmt":"2026-01-15T04:20:06","guid":{"rendered":"https:\/\/fmtsymbiodev.wpenginepowered.com\/conditions\/ibs"},"modified":"2026-02-16T13:39:17","modified_gmt":"2026-02-16T04:39:17","slug":"ibs","status":"publish","type":"page","link":"https:\/\/fmt.sym-biosis.co.jp\/en\/conditions\/ibs","title":{"rendered":"Irritable Bowel Syndrome (IBS)"},"content":{"rendered":"\n<p>Irritable Bowel Syndrome (IBS) is a condition where symptoms such as abdominal pain, diarrhea, and constipation persist chronically, even when no clear abnormalities are detected through standard medical examinations.<\/p>\n\n\n\n<p>It is thought to be caused by the intestinal tract becoming hypersensitive in its motility and perception, and is often exacerbated by stress and irregular lifestyle rhythms.<\/p>\n\n\n\n<p>IBS is prevalent across all age groups, from young adults to the elderly, and many individuals suffer from symptoms severe enough to significantly interfere with their professional or school life.<\/p>\n\n\n\n<p>Common treatments include intestinal regulators (probiotics), medications to adjust gastrointestinal motility, and psychological approaches to manage stress.<\/p>\n\n\n\n<p>While these treatments are intended to alleviate symptoms, they may recur once treatment is discontinued. Consequently, there is growing research into methods that address the root cause by balancing the gut environment.<\/p>\n\n\n\n<p>NanoGAS<sup>\u00ae<\/sup>-FMT is a procedure developed specifically for those seeking to fundamentally restructure their intestinal environment.<\/p>\n\n\n\n<p>We aim to correct imbalances in the intestinal flora (gut microbiota) and soothe hypersensitive intestinal reactions.<\/p>\n\n\n\n<p>As an approach that acts on the &#8220;biological state of the gut itself&#8221;\u2014an area often unreachable by conventional medicine\u2014research is progressing both in Japan and overseas.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Classification of Irritable Bowel Syndrome (IBS) and Characteristics of the Intestinal Flora<\/h2>\n\n\n\n<p>IBS is mainly classified into the following four types:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Constipation-predominant (IBS-C): Persistent constipation accompanied by abdominal bloating or discomfort.<\/li>\n\n\n\n<li>Diarrhea-predominant (IBS-D): Repeated sudden diarrhea and abdominal pain.<\/li>\n\n\n\n<li>Mixed type (IBS-M): Alternating cycles of constipation and diarrhea.<\/li>\n\n\n\n<li>Unclassified type (IBS-U): Cases that do not fit into a clear pattern.<\/li>\n<\/ul>\n\n\n\n<p>Recent studies have reported a trend toward decreased diversity along with an increase in gas-producing and inflammation-related bacteria in the intestinal flora of IBS patients. Such changes in the microbiomeare thought to be a primary reason why the nerves in the gut react hypersensitively to stimuli, withsymptoms frequently triggered by stress or dietary changes.<\/p>\n\n\n\n<p>In NanoGAS<sup>\u00ae<\/sup>-FMT, by addressing disruptions in the intestinal environment, we aim to stabilize the connection between the enteric nervous system and the brain (brain-gut correlation) and cultivate a &#8220;gut that does not react hypersensitively to stimuli.&#8221;<\/p>\n\n\n\n<p>In addition, because the NanoGAS<sup>\u00ae<\/sup> water used in the procedure is expected to reduce oxidative stress in the gut and minimize the burden on the mucous membranes, it is a procedure that is well-suited even for those with severe abdominal discomfort or those who have suffered from chronic diarrhea and constipation for many years.<\/p>\n\n\n\n<p>By rebuilding the intestinal environment, reports suggest the possibility of improving Quality of Life (QOL), such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Reduced abdominal pain and diarrhea in the morning<\/li>\n\n\n\n<li>Reduced anxiety when going out<\/li>\n\n\n\n<li>Alleviated malaise after meals<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What Fecal Microbiota Transplantation (NanoGAS\u00ae-FMT) Can Achieve<\/h2>\n\n\n\n<p>NanoGAS<sup>\u00ae<\/sup>-FMT aims to rectify the disruption of the intestinal flora in Irritable Bowel Syndrome (IBS) and soothe intestinal hypersensitivity.<\/p>\n\n\n\n<p>Unlike conventional FMT, NanoGAS\u00ae-FMT uses NanoGAS\u00ae water as the medium for the bacterial solution, enabling us to deliver beneficial bacteria to the gut gently and efficiently.<\/p>\n\n\n\n<p>In IBS, the &#8220;disrupted brain-gut correlation,&#8221; where the nerves in the gut react excessively to even slight stimuli, is considered a major factor.<\/p>\n\n\n\n<p>By restructuring the intestinal environment, NanoGAS\u00ae-FMT balances the communication between the gut and the brain, aiming to transform a &#8220;hypersensitive gut&#8221; prone to abdominal pain, gas, and unstable bowel movements into a &#8220;stable, calm gut.&#8221;<\/p>\n\n\n\n<p>In addition, by restoring the balance of intestinal bacteria, changes leading to the improvement of Quality of Life (QOL) have been reported, such as:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Normalization of the defecation pattern<\/li>\n\n\n\n<li>Reduced abdominal pain in the morning<\/li>\n\n\n\n<li>Reduced bloating and malaise after meals<\/li>\n<\/ul>\n\n\n\n<p>While NanoGAS<sup>\u00ae<\/sup>-FMT is not a pharmaceutical medicine, research is being conducted on it as a complementary method to enhance the gut&#8217;s inherent power to regain its balance.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The Process of Fecal Microbiota Transplantation for Irritable Bowel Syndrome (IBS)<\/h2>\n\n\n\n<p>NanoGAS<sup>\u00ae<\/sup>-FMT is performed safely following a consultation and examination by a doctor. The flow of the procedure is as follows:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Initial Consultation and Examination<br>We confirm the type of symptoms (IBS-C, IBS-D, IBS-M, etc.) and your medical history. Subsequently, a general blood test and an Intestinal Flora Balance Test are performed to determine eligibility for the procedure.<\/li>\n\n\n\n<li>Treatment Plan and Lifestyle Guidance<br>We determine the number of sessions and the duration of the procedure according to the state of the intestinal environment and lifestyle rhythm. Support for a gut-friendly lifestyle, including diet, sleep, and stress management, is also provided.<\/li>\n\n\n\n<li>Implementation of NanoGAS<sup>\u00ae<\/sup>-FMT<br>At a medical institution, the dedicated bacterial solution is transplanted into the intestine. The procedure can be performed on an outpatient basis using a method that minimizes irritation to the intestinal mucosa. After the procedure, you will keep a record in your digital diary (online diary) and share changes in your physical condition with the doctor.<\/li>\n\n\n\n<li>Follow-up<br>Progress reports are conducted at intervals such as 2 weeks, 3 months, and 6 months after the procedure to check the state of the gut and changes in symptoms. We recommend regular checks to prevent relapse.<\/li>\n<\/ol>\n\n\n\n<p>NanoGAS\u00ae-FMT does not typically bring about dramatic changes in a short period. However, as the stability of the intestinal environment is established, an increasing number of cases show gradual relief from discomfort that has been a concern for many years.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Medical Institutions Providing Irritable Bowel Syndrome (IBS) Care<\/h2>\n\n\n\n<p>NanoGAS<sup>\u00ae<\/sup>-FMT is performed at affiliated medical institutions belonging to The Association for Clinical Research of Fecal Microbiota Transplantation Japan. For example, the following medical institution provides careful counseling based on the progression of Irritable Bowel Syndrome:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Shirotani Bio Wellness Clinic (Kobe City, Hyogo Prefecture)<br>Familiar with nutritional therapy and immunotherapy, they perform procedures based on the relationship between the intestinal environment and general condition.<\/li>\n<\/ul>\n\n\n\n<p>At all medical institutions, bacterial solutions manufactured in dedicated facilities based on a common protocol are used. Since the types and causes of IBS symptoms vary from person to person, we recommend that you first undergo a consultation with a doctor and discuss a treatment plan that suits you.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>For a list of clinics nationwide, please also see our guide to affiliated medical institutions. You can search by region or medical department. (Link: <a href=\"https:\/\/fmt.sym-biosis.co.jp\/transplantation\/partner\">https:\/\/fmt.sym-biosis.co.jp\/transplantation\/partner<\/a>)<\/li>\n\n\n\n<li>For estimates on fees and private practice, please see <a href=\"https:\/\/fmt.sym-biosis.co.jp\/en\/transplantation\/costs\" target=\"_blank\" rel=\"noopener\" title=\"\">the transplant fee page<\/a> for fecal microbiota transplantation.<\/li>\n<\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Frequently Asked Questions Regarding Irritable Bowel Syndrome (IBS)<\/h2>\n\n\n\n<p>Q: Does NanoGAS<sup>\u00ae<\/sup>-FMT stop symptoms like a medicine?<\/p>\n\n\n\n<p>A: NanoGAS<sup>\u00ae<\/sup>-FMT is not a medicine, but a procedure to balance the intestinal environment. By restoring the balance of the gut microbiota, there are cases where symptoms such as abdominal pain and unstable bowel movements gradually ease.<\/p>\n\n\n\n<p>Q: How soon can I feel the effects?<\/p>\n\n\n\n<p>A: While there are individual differences, many people experience changes in their physical condition in approximately 1 to 3 months. Since intestinal function recovers gradually, it is important to observe the progress continuously without rushing.<\/p>\n\n\n\n<p>Q: How can I prevent recurrence?<\/p>\n\n\n\n<p>A: To stabilize the intestinal environment, diet, sleep, and stress management after the procedure are also important. By adjusting your lifestyle rhythm under a doctor&#8217;s guidance, it becomes easier to prevent relapse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Irritable Bowel Syndrome (IBS) Related Columns and Materials<\/h2>\n\n\n\n<p>We also publish columns explaining the relationship between IBS and the intestinal environment, as well as lifestyle habits to prevent relapse.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Easy-to-understand explanation of the brain-gut correlation (Blog link coming soon)<\/li>\n\n\n\n<li>Recommended diet for Irritable Bowel Syndrome: Addressing gas and stress types (Blog link coming soon)<\/li>\n\n\n\n<li>The science of probiotics and the intestinal environment (Blog link coming soon)<\/li>\n<\/ul>\n\n\n\n<p>Furthermore, regarding the safety of the procedure and clinical research data, it is also introduced in the Clinical Study Results (IBS edition).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Summary of Irritable Bowel Syndrome (IBS)<\/h2>\n\n\n\n<p>To improve Irritable Bowel Syndrome, it is essential not only to use medication and psychological approaches but also to rebuild the intestinal environment. NanoGAS<sup>\u00ae<\/sup>-FMT aims to nurture a &#8220;gut that does not experience recurring relapses&#8221; as a new complementary procedure for this purpose.<\/p>\n\n\n\n<p>For consultations regarding symptoms or further details, please first contact a handling medical institution. Achieving a calm gut should be the first step toward living your daily life with peace of mind.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Irritable Bowel Syndrome (IBS) is a condition where symptoms such as abdominal pain, diarrhea, and constipation persist chronically, even when no clear abnormalities are detected through standard medical examinations. It is thought to be caused by the intestinal tract becoming hypersensitive in its motility and perception, and is often exacerbated by stress and irregular lifestyle [&hellip;]<\/p>\n","protected":false},"author":5,"featured_media":0,"parent":4607,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-4611","page","type-page","status-publish","hentry"],"acf":[],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/fmt.sym-biosis.co.jp\/en\/wp-json\/wp\/v2\/pages\/4611","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/fmt.sym-biosis.co.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/fmt.sym-biosis.co.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/fmt.sym-biosis.co.jp\/en\/wp-json\/wp\/v2\/users\/5"}],"replies":[{"embeddable":true,"href":"https:\/\/fmt.sym-biosis.co.jp\/en\/wp-json\/wp\/v2\/comments?post=4611"}],"version-history":[{"count":0,"href":"https:\/\/fmt.sym-biosis.co.jp\/en\/wp-json\/wp\/v2\/pages\/4611\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/fmt.sym-biosis.co.jp\/en\/wp-json\/wp\/v2\/pages\/4607"}],"wp:attachment":[{"href":"https:\/\/fmt.sym-biosis.co.jp\/en\/wp-json\/wp\/v2\/media?parent=4611"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}